May 17, 2006

Studies unclear whether spinal cement procedure improves back pain

Back in January I wrote about an experiment where female baboons had several vertebrae destroyed and then filled with commercially available bone cement compounds.

In 2002 and again in 2004, the FDA issued warnings about serious complications related to the use of bone cements as treatment for spinal compression fractures .

Last week, a meta-analysis revealed that the use of bone cements doesn't appear to have any significant positive effect for reducing pain in human patients with compression fractures caused by osteoporosis or certain types of tumors. (Note that the monkeys used in the earlier experiment did not have either condition, but that their vertebrae were surgically destroyed.) I fear that these new results will give rise to more monkey experiments.

-Monkeys are caged their whole lives and have extremely limited opportunities for any movement at all, let alone exercise. This undoubtedly has effects for bone and joint status.
-Monkeys are not bipedal and thus locomotion and orientation of the spine (pressure, torque) are different both when stationary and in motion.
-Monkey biomechanics and anatomy differ significantly from humans.

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