Drug trial rules 'should change'

BBC NEWS Health Drug trial rules 'should change'

"In the light of the TGN 1412 incident, there is a need to look at the future safety of clinical trials involving novel and potentially higher risk drugs "

Sure...but are we to think that the earliest human trials are the best and only place to institute change? Or that registering clinical trials once they are underway will solve our problems? Or that forcing financial disclosure statements of authors who publish trial results in medical journals will make us all safe? Our current system is broken in several places, and there is no band-aid large enough to fix it.

Safety requires change *upstream* as well. What happens before drugs get to clinical trials and is current practice effective?