Life is full of surprises (and dead rats)

The Future is Unwritten. In the Pipeline:

"I had a project once where adding a single methyl group to the a molecule changed it from being an infallible overnight rodent-killer to something that could be given for two weeks straight at ten times the normal dose. Clearly we managed to slip out of whatever protein target it was dealing death, but these things can't be modeled or predicted."

And the fun doesn't start or stop there. First you have the surprises of mice and maybe dogs.

And after the rats you might get something really jaw-droppingly unexpected, like say dead monkeys. That's something that will really make you slap your forehead or stroke your chin in confusion.

Then, after all of that is said and done...you can get the really unexpected "eureka" of something like a TGN1412. Sometimes you have to wait a while...for something like a Vioxx.